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 You can find in this section all the publications and press releases of the project consortium.


Systems-level temporal immune-metabolic profile in Crimean-Congo hemorrhagic fever virus infection, Anoop T. Ambikana, Nazif Elaldib, Sara Svensson- Akusjärvia, et al., Proceedings of the National Academy of Sciences (PNAS)    2023    120(37):e2304722120 - Read more

Accelerated DNA vaccine regimen provides protection against Crimean-Congo hemorrhagic fever virus challenge in a macaque model, David W. Hawman; Kimberly Meade-White; Shanna Leventhal; et al., Molecular Therapy    2023    31(2):387-397 - Read more


Comparison of Crimean-Congo Hemorrhagic Fever Virus and Aigai Virus in Life Cycle Modeling Systems Reveals a Difference in L Protein Activity, Matthew J. Pickin; Stéphanie Devignot; Friedemann Weber; et al., Journal of Virology    2022    96(13):e0059922 - Read more

Nucleoside-Modified mRNA Vaccines Protect IFNAR–/– Mice against Crimean-Congo Hemorrhagic Fever Virus Infection, Sofia Appelberg; Lijo John; Norbert Pardi; et al., Journal of Virology   2022    96(3):e0156821 - Read more

Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target; Ujjwal Neogi; Nazif Elaldi; Sofia Appelberg; et al., eLife   2022    19:11:e76071 - Read more


Deciphering Antibody Responses to Orthonairoviruses in Ruminants; Julia Hartlaub, Markus Keller, Martin H. Groschup, Microorganisms  2021  9(7):1493 - Read more

Diagnosis and Pathogenesis of Nairobi Sheep Disease Orthonairovirus Infections in Sheep and Cattle; Julia Hartlaub, Benjamin Gutjahr, Christine Fast, et al.;  Viruses    2021    13(7):1250 - Read more

Cross-Reaction or Co-Infection? Serological Discrimination of Antibodies Directed against Dugbe and Crimean-Congo Hemorrhagic Fever Orthonairovirus in Nigerian Cattle; Julia Hartlaub, Oluwafemi B. Daodu, Balal Sadeghi,et al. ; Viruses    2021    13(7):1398 - Read more

Experimental Challenge of Sheep and Cattle with Dugbe Orthonairovirus, a Neglected African Arbovirus Distantly Related to CCHFV; Julia Hartlaub, Felicitas von Arnim, Christine Fast, et al.;  Viruses    2021    13(3):372 - Read more


Recombinant Rift Valley fever viruses encoding bluetongue virus (BTV) antigens: Immunity and efficacy studies upon a BTV-4 challenge; Sandra Moreno; Eva Calvo-Pinilla; Stephanie Devignot; et al.;    PLOS Neglected Tropical Diseases    2020    14(12):e0008942 - Read more

The interplays between Crimean-Congo hemorrhagic fever virus (CCHFV) M segment-encoded accessory proteins and structural proteins promote virus assembly and infectivity; Natalia Freitas; Margot Enguehard; Solène Denolly; et al. ;  PLOS Pathogens    2020    16(9):e1008850 - Read more

ISG15 overexpression compensates the defect of Crimean-Congo hemorrhagic fever virus polymerase bearing a protease-inactive ovarian tumor domain; Stephanie Devignot; Thilo Kromer; Ali Mirazimi; et al.;   PLOS Neglected Tropical Diseases    2020    14(9):e0008610 - Read more

Sheep and Cattle Are Not Susceptible to Experimental Inoculation with Hazara Orthonairovirus, a Tick-Borne Arbovirus Closely Related to CCHFV; Julia Hartlaub, Felicitas von Arnim, Christine Fast, et al.;    Microorganisms    2020    8(12):1927 - Read more


Epitope-mapping of the glycoprotein from Crimean-Congo hemorrhagic fever virus using a microarray approach; Amanda Fritzen, Christian Risinger, Gulay Korukluoglu, et al. ; PLOS Neglected Tropical Diseases    2018    12(7):e0006598 - Read more

Second International Conference on Crimean-Congo Hemorrhagic Fever ; Jessica R. Spengler, Dennis A. Bente, Mike Bray, et al.; Antiviral Research    2018    150:137-147 - Read more


Immunization with DNA Plasmids Coding for Crimean-Congo Hemorrhagic Fever Virus Capsid and Envelope Proteins and/or Virus-Like Particles Induces Protection and Survival in Challenged Mice, Jorma Hinkula, Stéphanie Devignot, Sara Åkerström, et al.,    Journal of Virology    2017    91(10):e02076-16 - Read more