You can find in this section all the publications and press releases of the project consortium.
2023
Systems-level temporal immune-metabolic profile in Crimean-Congo hemorrhagic fever virus infection, Anoop T. Ambikana, Nazif Elaldib, Sara Svensson- Akusjärvia, et al., Proceedings of the National Academy of Sciences (PNAS) 2023 120(37):e2304722120 - Read more
Accelerated DNA vaccine regimen provides protection against Crimean-Congo hemorrhagic fever virus challenge in a macaque model, David W. Hawman; Kimberly Meade-White; Shanna Leventhal; et al., Molecular Therapy 2023 31(2):387-397 - Read more
2022
Comparison of Crimean-Congo Hemorrhagic Fever Virus and Aigai Virus in Life Cycle Modeling Systems Reveals a Difference in L Protein Activity, Matthew J. Pickin; Stéphanie Devignot; Friedemann Weber; et al., Journal of Virology 2022 96(13):e0059922 - Read more
Nucleoside-Modified mRNA Vaccines Protect IFNAR–/– Mice against Crimean-Congo Hemorrhagic Fever Virus Infection, Sofia Appelberg; Lijo John; Norbert Pardi; et al., Journal of Virology 2022 96(3):e0156821 - Read more
Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target; Ujjwal Neogi; Nazif Elaldi; Sofia Appelberg; et al., eLife 2022 19:11:e76071 - Read more
2021
Deciphering Antibody Responses to Orthonairoviruses in Ruminants; Julia Hartlaub, Markus Keller, Martin H. Groschup, Microorganisms 2021 9(7):1493 - Read more
Diagnosis and Pathogenesis of Nairobi Sheep Disease Orthonairovirus Infections in Sheep and Cattle; Julia Hartlaub, Benjamin Gutjahr, Christine Fast, et al.; Viruses 2021 13(7):1250 - Read more
Cross-Reaction or Co-Infection? Serological Discrimination of Antibodies Directed against Dugbe and Crimean-Congo Hemorrhagic Fever Orthonairovirus in Nigerian Cattle; Julia Hartlaub, Oluwafemi B. Daodu, Balal Sadeghi,et al. ; Viruses 2021 13(7):1398 - Read more
Experimental Challenge of Sheep and Cattle with Dugbe Orthonairovirus, a Neglected African Arbovirus Distantly Related to CCHFV; Julia Hartlaub, Felicitas von Arnim, Christine Fast, et al.; Viruses 2021 13(3):372 - Read more
2020
Recombinant Rift Valley fever viruses encoding bluetongue virus (BTV) antigens: Immunity and efficacy studies upon a BTV-4 challenge; Sandra Moreno; Eva Calvo-Pinilla; Stephanie Devignot; et al.; PLOS Neglected Tropical Diseases 2020 14(12):e0008942 - Read more
The interplays between Crimean-Congo hemorrhagic fever virus (CCHFV) M segment-encoded accessory proteins and structural proteins promote virus assembly and infectivity; Natalia Freitas; Margot Enguehard; Solène Denolly; et al. ; PLOS Pathogens 2020 16(9):e1008850 - Read more
ISG15 overexpression compensates the defect of Crimean-Congo hemorrhagic fever virus polymerase bearing a protease-inactive ovarian tumor domain; Stephanie Devignot; Thilo Kromer; Ali Mirazimi; et al.; PLOS Neglected Tropical Diseases 2020 14(9):e0008610 - Read more
Sheep and Cattle Are Not Susceptible to Experimental Inoculation with Hazara Orthonairovirus, a Tick-Borne Arbovirus Closely Related to CCHFV; Julia Hartlaub, Felicitas von Arnim, Christine Fast, et al.; Microorganisms 2020 8(12):1927 - Read more
2018
Epitope-mapping of the glycoprotein from Crimean-Congo hemorrhagic fever virus using a microarray approach; Amanda Fritzen, Christian Risinger, Gulay Korukluoglu, et al. ; PLOS Neglected Tropical Diseases 2018 12(7):e0006598 - Read more
Second International Conference on Crimean-Congo Hemorrhagic Fever ; Jessica R. Spengler, Dennis A. Bente, Mike Bray, et al.; Antiviral Research 2018 150:137-147 - Read more
2017
Immunization with DNA Plasmids Coding for Crimean-Congo Hemorrhagic Fever Virus Capsid and Envelope Proteins and/or Virus-Like Particles Induces Protection and Survival in Challenged Mice, Jorma Hinkula, Stéphanie Devignot, Sara Åkerström, et al., Journal of Virology 2017 91(10):e02076-16 - Read more